The DoseFinding package provides functions for the design and analysis
of dose-finding experiments (with focus on pharmaceutical Phase
II clinical trials). It provides functions for: multiple contrast
tests, fitting non-linear dose-response models (using Bayesian and
non-Bayesian estimation), calculating optimal designs and an
implementation of the MCPMod methodology (Pinheiro et al. (2014)
<doi:10.1002/sim.6052>).
| Version: |
1.0-2 |
| Depends: |
lattice, mvtnorm, R (≥ 2.15.0) |
| Suggests: |
numDeriv, Rsolnp, quadprog, parallel, multcomp, ggplot2, knitr, rmarkdown, MASS, testthat |
| Published: |
2021-10-03 |
| Author: |
Bjoern Bornkamp 
[aut, cre],
Jose Pinheiro [aut],
Frank Bretz [aut],
Ludger Sandig [aut] |
| Maintainer: |
Bjoern Bornkamp <bbnkmp at mail.de> |
| License: |
GPL-3 |
| NeedsCompilation: |
yes |
| Materials: |
ChangeLog |
| In views: |
ClinicalTrials, ExperimentalDesign |
| CRAN checks: |
DoseFinding results |