replicateBE: Average Bioequivalence with Expanding Limits (ABEL)

Performs comparative bioavailability calculations for Average Bioequivalence with Expanding Limits (ABEL). Implemented are 'Method A' / 'Method B' and the detection of outliers. If the design allows, assessment of the empiric Type I Error and iteratively adjusting alpha to control the consumer risk. Average Bioequivalence - optionally with a tighter (narrow therapeutic index drugs) or wider acceptance range (South Africa: Cmax) - is implemented as well.

Version:	1.1.3
Depends:	R (≥ 3.5.0)
Imports:	readxl (≥ 1.0.0), PowerTOST (≥ 1.5.3), lmerTest, nlme, pbkrtest, graphics, grDevices
Suggests:	knitr, rmarkdown, testthat, devtools
Published:	2022-05-02
Author:	Helmut Schütz [aut, cre], Michael Tomashevskiy [ctb], Detlew Labes [ctb]
Maintainer:	Helmut Schütz <helmut.schuetz at bebac.at>
BugReports:	https://github.com/Helmut01/replicateBE/issues
License:	GPL (≥ 3)
URL:	https://github.com/Helmut01/replicateBE
NeedsCompilation:	no
Materials:	README NEWS
In views:	ClinicalTrials
CRAN checks:	replicateBE results

Documentation:

Reference manual:	replicateBE.pdf
Vignettes:	replicateBE

Downloads:

Package source:	replicateBE_1.1.3.tar.gz
Windows binaries:	r-devel: replicateBE_1.1.3.zip, r-release: replicateBE_1.1.3.zip, r-oldrel: replicateBE_1.1.3.zip
macOS binaries:	r-release (arm64): replicateBE_1.1.3.tgz, r-oldrel (arm64): replicateBE_1.1.3.tgz, r-release (x86_64): replicateBE_1.1.3.tgz, r-oldrel (x86_64): replicateBE_1.1.3.tgz
Old sources:	replicateBE archive

Linking:

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