Quickly computes polygenic scores from GWAS summary statistics of either case-control or quantitative traits, without LD matrix computation or parameter tuning. Reales,G., Vigorito, E., Kelemen,M., Wallace,C. (2021) <doi:10.1101/2020.07.24.220392> "RápidoPGS: A rapid polygenic score calculator for summary GWAS data without a test dataset".
Version: | 2.2.0 |
Depends: | R (≥ 4.0), data.table, RCurl, curl |
Imports: | dplyr (≥ 1.0.6), GenomicRanges (≥ 1.42.0), IRanges (≥ 2.24.1), bigsnpr (≥ 1.8.1), coloc (≥ 5.1.0), bigreadr (≥ 0.2.4) |
Suggests: | knitr, rmarkdown |
Published: | 2022-06-15 |
Author: | Guillermo Reales [aut, cre], Chris Wallace [aut], Olly Burren [ctb] |
Maintainer: | Guillermo Reales <gr440 at cam.ac.uk> |
License: | GPL-3 |
NeedsCompilation: | no |
Citation: | RapidoPGS citation info |
Materials: | README NEWS |
CRAN checks: | RapidoPGS results |
Reference manual: | RapidoPGS.pdf |
Vignettes: |
Computing a PGS using RápidoPGS-multi Computing a PGS using RápidoPGS-single and GWAS catalog |
Package source: | RapidoPGS_2.2.0.tar.gz |
Windows binaries: | r-devel: RapidoPGS_2.2.0.zip, r-release: RapidoPGS_2.2.0.zip, r-oldrel: RapidoPGS_2.2.0.zip |
macOS binaries: | r-release (arm64): RapidoPGS_2.2.0.tgz, r-oldrel (arm64): RapidoPGS_2.2.0.tgz, r-release (x86_64): RapidoPGS_2.2.0.tgz, r-oldrel (x86_64): RapidoPGS_2.2.0.tgz |
Old sources: | RapidoPGS archive |
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